1. Glossary
  2. GLP-1 receptor agonist

GLP-1 receptor agonist

A GLP-1 receptor agonist is a type of medicine that acts like glucagon-like peptide-1, a hormone the body releases after eating. These medicines can increase insulin release when blood sugar is high, reduce glucagon, slow stomach emptying and affect appetite and feelings of fullness.

Examples include semaglutide and liraglutide. In Australia, different products are approved for different uses: some treat type 2 diabetes, while others are approved for chronic weight management. A brand approved for diabetes is not automatically approved for weight loss, even when the active ingredient is similar.

GLP-1 receptor agonists are prescription medicines and are not insulin. Common side effects are gastrointestinal, but serious side effects can occur. A doctor assesses whether a particular medicine is clinically appropriate and monitors response, side effects and other health considerations.

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